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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbef534dc2df21eaaed966aaef8fa3ecd3fa274721ff3786ed97ba367a3c69d3' 
  AND token = 'Z0QMByvD56sYKpJ+3FR4rMS4Hn2kIVBanHJS6M7eBag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}