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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '147cfa19c53d2a8d370c0e391d91c588dd22d56b55316c9b9e34fa4fecb7defc' 
  AND token = 'ZxGuSXFvRuOseu6kZrmSPn0X5cLS0tCN4Eob0rV8Krs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}