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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55c81db4ad3ac08cb20a043170f6735df446e115b5570dae4e02c1dc9183faea' 
  AND token = '+zd++T+rWNIMOB0ZTbyEskZt6OdBxQZW7Xu9e6h3WMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}