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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0912ca759c4aaa3ba411774265daed3e724a98a92ef0f8d078e831062ec8e9da' 
  AND token = 'EdaAWeXeFr+o6ff1zt4n9AHW1ln/8ELgwG/A6m4GS2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}