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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a81616adac903477e44a1750c6ca68c2adf202ff09509e396c7346420e31f8' 
  AND token = 'x2wmtmq07is6NLVZ8fWlffwDs/jYZNzCnw3rN/IbK2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}