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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9277ee3952f3263e3c487cab8f8c99c1c4b3d6057d580bde4e28539623e97e01' 
  AND token = 'FS429WC99vIM282BFjQkUkVIxI8Wmk65jli39TQuoxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}