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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fed9206ddc0f7632fc793c5844fc06a8fd42f1c16f1da8a0da1552fece481b4' 
  AND token = 'kXJz+Hg8D8yBawJmcjFOUkPBc5ydez2PjNkYDWQq2jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}