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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3430a09f11c33705b5521cad27d0201d34702d05300b38f71e69726dbdb464e' 
  AND token = '55ew09VEDc2+iFP0vfWiS389ncG7zVMb9CZz7K19vgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}