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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e218738b64ab5504618aab2002441c3fa97d916aebfbac595c36f4d7fea8f0f1' 
  AND token = 'D32CVuPVcEWIJUMJgU6CiGegjLd2QY5deeTc9s1qI1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}