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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3e27235ff37c8c9d827c36e35497c76bdd72540410d2f5a2519267e14fe085b' 
  AND token = '5kQJc9IyDm85o7X14APsV3328LvEe5z04lez0F+lHe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}