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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea8d3374772091a26c675c16e33125296e639ee2f64aa914abf278df8173200c' 
  AND token = 'aQOx9v/gyAG1U2lN+yqmpNnQDfWFta/M6KQ70MYgrH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}