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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99d082f082c9704f6985003518f739633a64cc749f49f16c9b09faefdcbd2cc' 
  AND token = 'cP6eZzVgbcaffIsiowkDc6n4oq/zKNQBgrt2KdhV444=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}