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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05c5732016ff0777a1029478d58a5e1216fb91d4d417f8341247fc56c4b7441d' 
  AND token = 'P286JK013BKx+fPQtfWIdz5dJWaCeK2ncZOtitG0gL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}