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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7824ee367a1e38b26a1cf0055bed50e43fb028c0338d98103c0f75fdbdf073' 
  AND token = 'fwU/V4F9gpPqIz5Coo3jDtA1Lor3KFIYkI207Cz55LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}