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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a3b9e5d39b762f8815224696150bc878dd0e0956323cb86a76647fd4b22d23' 
  AND token = '1aDZP5LMF/zzCgWzEYMf037p4AXH9Q7aeKoFB+3Sre4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}