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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd443991aa421ce0a7b54bc67b39a03c2166f7fc34b523cf683fdc4b34a18bd57' 
  AND token = 'lOeCjC64XxgyuCkBaQQqufQ4qBbeDy1pL9O79PfTZhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}