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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bee4a34c02204e4ba1b58598cdd7b008bd3aa79a3496c79dc6f6c99ae550137' 
  AND token = 'zWM97JO/Zlvdoy/v0I5sKjN4f7g4h1WT9QAD9BUVSbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}