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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b27a137c54715ab50a402cfeda61da18e1b797d084b081d99d0536a5a14e54' 
  AND token = 'iUTOtnwNOzztI8jCNNJcTxNrTRJLklmY+HC8UIn+D1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}