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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9330470efdac0a44d5771be82b41426a7cf32c78c65f1f18d7f198ce0486d49e' 
  AND token = 'znnY/TiB3S173dW2VIUQHoH1EUrOW7eWuOEmEtJGfBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}