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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8662a0e3d819770d2c211564235041f5f706d69bc9e1ab5e47e044eb895786' 
  AND token = 'u1HoTn4WoXG08TyoDUvU9sjaGFy6G+cwDKMbIUY9gSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}