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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535e95dfa8bc5c726dd504d81468548e2cd6260816493f3ea4ee7ffc24b54d26' 
  AND token = 'EBh2UM9Mno46arDhdrOYRjKQI2f0sHni6l5YLxqNE5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}