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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37306b1555a1f73725470f43580153389886c880cdf4df2b680d58243b749cd8' 
  AND token = 'Uqoi0E+9psAA5a05njvGkIfAYvo2G1ai6ycEIS6S4Kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}