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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a50a9121a4b2405db63bbc06a81ac6249c04792e6d450288c4a2fdce437eaab' 
  AND token = 'xRPxIbsbJ7eQllTmAnoHj7zFFe5dhsCN1Vgb17uJdrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}