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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a518fce6dd7489cb677e6298605224b7167d5de31a97d6466f01088bfe03e8' 
  AND token = 'XquhBawuWTTpATxp2/x253Dq8Rd0l7vAnZIo6Pz097Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}