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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6da2358ca21e6fe159e7f0b4804b9dcb8d3208bc8909e479868b84b581a591ce' 
  AND token = 'uKbfdnbn48R63lfpEdWzs2/RSr+iyheu2W6fh3z3K8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}