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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65968a33d53fa5c8463e37402cefd551569101abec82de5a714370089b14f11c' 
  AND token = 'dNTXWE3GtZNMZ5wB4G5hlgms4rSjkZTQuwrXjSsc4JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}