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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '402eac21a4913c527f5077da49f7b1537337d8581a591c1331e69d31b829d54c' 
  AND token = '01Vtm9dWVswvDQWcrSiU7U3L04X/edfjpC/4/iOxKeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}