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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a879b4d30ad33ac199d309460a71b6ae5bb24aa66d7719a725d2a074a2f3896f' 
  AND token = 'rZHY4UZ0cTjuD+IxkFn8tlWCYw61xbewEsBQgR059Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}