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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9b81afc149d3abff9e047b21418d311c841ee181d0db5f77259872792a66aca' 
  AND token = 'E9EQDpXMx2yT1PQzja9Mm4OuGOdhmquqB7fd0jsjWYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}