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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d1476402258505ea564d03e5b4eb01786bfbbb72519b7092e20da49875289a' 
  AND token = 'qWFGZ4M5I1MxH20r18sZ4xBoNJedehTD+1PsO4K8drA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}