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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7b7e601bc4dcd9c3d3562230569d9813570f7a7ea968ef22cdb4221e1cf87f' 
  AND token = 'EE/pqrApVcqvUugA+ocSoUdhJcE4ZYuJ50Ap0ZP1YQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}