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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ec12a2d2c99e1cbbcb36bceac2b5321ea9e15bf583712e3338319c03345e18e' 
  AND token = 'rrX827OWPGJSJTS+JExZzfq2Hg6GzX3EJzYlzdqmzWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}