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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d9db6fd080a8c531c29e59fc642d40efd9153529654f0fbc69acf66c9cc6392' 
  AND token = 'mD4ZlUI04nt5BxHa3ZTPCQj8M65Im+Og5qLeyq4UHH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}