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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd46cbb1fb9d69138666768c15497bc07c3e2d14c5d100e6d94d3beebf1bf9f44' 
  AND token = 'Z/q7tMZLAZ503tUgo5MvR3KlfdedA2pawULnSbnN8LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}