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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '600c06252ba2c4ef1b9f49554e48ea7788f94d96d1e18475283a8f669b2df513' 
  AND token = '2MxwMDPQFhKnb03xpqnAS/u6WEad5DtHnuRRrYExCxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}