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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8262a95e14734f74fcacc52f560c6b424f74e097d4f43cfa38526c8b7f356d65' 
  AND token = 'RTVjj8zpAmWdEk+kkcRck+4PC1gTHVZTTRFTEcrnC44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}