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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2993a8b117b73bfa30c9faabcbf9c039e403c55c9321db1de9e676ce3ead4847' 
  AND token = 'vVasx5URS002KxuilkRlkuzlSDY6vU+xS/0+Un7HwVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}