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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f935dc04b41cde45a8952b54c476328e65be4c7876f21fe555ca1113e06211' 
  AND token = 'kdMvZeV9xDw9lUbPxTNfzE8XZqDjqn+R8+2Xu1coJ8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}