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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2206e932bc66235bd17fdc50328bb78678ac094d9715e4d251da0f9f6ad294e' 
  AND token = 'mWs3eHx0PCvESUMpgbcG6RLHzLuPK3Uj3mEPUbOmrYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}