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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c6a8163f73d5efcab30cb9871c43b21cf85ba1678fd1b0184025019a894260' 
  AND token = 'OQV+r+GRba6E/ukQrvDdltSbjXOXFK3EWIx3F6jEK0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}