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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8d49422003f644001a76bfeb938e6e475122eb5deab6b4af67f372874c4715' 
  AND token = '0LyGGeSmTeJ632CbKL5C79ebQ4qq1W6AcIyh96TDrUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}