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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3502a14e4afc24e169a5789bf66be08169ffff60d5b2d319a24288c33ec3c7' 
  AND token = 'uDz4we60sFaI8WOpDFIi70uP0QD73v0gBXKbEvaVy6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}