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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd39ccf9b8ee6421e371baecc84cb2e0cf64c0163158f3cfde6c2914df0683f' 
  AND token = 'DdUvDxRVs/fjQz8HrdHoRql0nOYBNTYhrFA1k6UhQYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}