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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3b4d7253bcda8a9fd8d34863fc2ec6036c4dc19a662da731de0a33fe0a59396' 
  AND token = 'xIpydzKH1PteZp+qXYmUy0AHSsBxpSzU++5EhKkh6Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}