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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb18f8f0f13a23f91a21535083a0d39ba8df29406d1ccf50d1553bb6fe5b2914' 
  AND token = 'OEF6WCNpB6qGOGF+IuHlg9ND1sB6TixzvFb0aqQTmvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}