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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c61a3c280c601cbff02c9c011c94dc1ad46585a3a3c7773ed40441ac053560f' 
  AND token = '2GGUESxyzOMp63qUE1B5YzAsmzk0cd6FG7qwbGS6jyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}