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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10cc93f408871e1b04fea82354eeb03ab365f8f4dff6746786b2a8f9205e7f7' 
  AND token = 'b2nOl0h3sUbVzb+O+2T2Fhmow09JGOO9Yp2kCNLPiWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}