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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffaf6f37b335bffc62bc96edcc5b9c9cd71e537bcb315f153a6bbdf438411a82' 
  AND token = 'frILLBoUo1MxfnWAV5wkGQ7Hqh23jSxc+Y3h3JHM2Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}