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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8451854a458a0a35f79c24726b5cb4f517c0a45da98e187f52b8fd696b82f4df' 
  AND token = '3yN48vrlNBV08bFVJ+u2lpM3zpMj7Ny4Ij3nRVH1308=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}