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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d88b79e8e5fc1b17a793d22d656baa4c65646dada5908587c71ee2c409bd4d9' 
  AND token = 'zEIf9MqcIKSkmH5fBXgte/UyFRAclvZDChqlfi+2aUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}